ABITEC's excipients have a wide range of application capabilities including for use in lubrication of direct-compression tablet formulations. Proper lubrication during direct compression tableting is vital to reducing friction and the wear on punches and dies. In addition to their excellent lubrication properties, ABITEC's excipients can also be employed in sustained release, taste-masking, abuse-deterrence and solubility applications.
Featured Product: Sterotex® NF
LUBRICATING DRY BINDER FOR DIRECT COMPRESSION TABLETING
STEROTEX NF (Hydrogenated Vegetable Oil Type I) functions both as a boundary lubricant and as a dry binder. The oleaginous nature of Sterotex NF provides boundary lubrication to direct-compression tableting blends reducing ejection force. Sterotex NF also plastically deforms at relatively low compression pressures providing increased tablet hardness and reduced tablet friability making it an ideal dry binder for direct compression tableting operations.
- Freely flowing
- Plastically deforming at low compression pressures
- Provides boundary lubrication and reduces ejection force
- Economical compared to other dry binders
- Reduced effect on disintegration times compared with magnesium stearate
Sterotex is designed to be dry blended into pharmaceutical tablet formulations to provide for lubrication during direct compression tableting. Additionally, Sterotex can be melt processed to generate the active containing multi-particulates with sustained-release, abuse-deterrent, moisture barrier, and/or taste masking characteristics.
The Sterotex line is reproducibly manufactured by the prilling (spray-chilling) of selected, hydrogenated vegetable oils.
|Product Name||Chemical Name||CAS Number|
|Sterotex HM, NF||Hydrogenated Soybean Oil||8016-70-4|
|Sterotex K, NF||Hydrogenated Vegetable Oil (soybean & castor)||8016-70-4,
|Sterotex NF||Hydrogenated Cottonseed Oil||68334-00-9|
Captex medium-chain esters are preferred lipophilic vehicles and solvents, used alone or in combination with other excipients, in the development of solution, suspension, emulsion and microemulsion formulations for various delivery systems. Captex is most well-known as an excellent solubilizer and carrier for actives, however, its unique properties also make it very beneficial in lubricant and processing of soft gel and hard gelatin capsules.
|Captex 300 EP/NF||Glycerol Tricaprylate/caprate||65381-09-1, or
|Captex 355 EP/NF||Glycerol Tricaprylate/caprate||65381-09-1, or
CAPTEX®, and STEROTEX® are registered trademarks of ABITEC Corporation. All information and statements given on this website are believed to be accurate at the time of publication. However, neither ABITEC Corporation nor any of their affiliates make any representations or warranty with respect thereto, including, but not limited to, any results obtained in the processing of the products by customers or any third party. All information and statements are intended for persons having the required skill and know-how and do not relieve the customer or user from verifying the suitability of information and statements given for a specific purpose prior to use of the products. It is entirely the obligation of the customer or user to comply with applicable laws and regulations, and also with all patent or other intellectual property rights of third parties. ABITEC CORPORATION EXPRESSELY DISCLAIMS ANY REPRESENTATIONS OR WARRANTIES OF ANY KIND, WHETHER EXPRESSED OR IMPLIED, AS TO THE ACCURACY, CURRENCY, COMPLETENESS AND/OR THE MERCHANTABILITY OR FITNESS OF A PARTICULAR PURPOSE OF ANY INFORMATION CONTAINED ON THIS WEBSITE AND/OR PRODUCT DESCRIBED OR PROMOTED ON THIS WEBSITE, INCLUDING WARRANTIES WITH RESPECT TO INFRINGEMENT OF ANY PATENT, COPYRIGHT, OR OTHER RIGHTS OF A THIRD PARTY. We reserve the right to change product specifications and specified properties of the products without prior notice.