Topical & Transdermal

Lipid-based drug delivery is an effective method for incorporating insoluble actives in topical and transdermal dosage forms by carrying the active in an oil in water emulsion that can be added into a cream or gel.  Additionally, many of ABITEC’s functional lipids, when incorporated in topical dosage forms, can provide for increased transdermal delivery of actives.

Improved Solubility & Enhanced Permeation

Diffusion of active ingredients through the skin is affected by many factors, including the physiochemical nature of the respective active ingredient and hydration of the respective layers of the skin.  ABITEC functional lipids can both enhance the solubility of insoluble actives intended for transdermal delivery, as well as increase the hydration of the skin layers improving active permeability through the skin.  Complete solubility of the active is achieved by incorporating the active in a solubilizing lipid vehicle or in an oil in water emulsion, which maintains the active in a solubilized state.  Simultaneously, the functional lipid vehicle or emulsion provides a moisturizing effect for the skin layers resulting in an increase in diffusion of the active across the layers of the skin. 

Our portfolio Includes:

  • Solubilizers & Skin Penetration Enhancers
  • Emulsifiers
  • Film formers
  • High diffusivity
  • Translocation
  • Stabilizers & Co-Emulsifiers

Related Products


This line of highly-functional, highly reproducible medium and long chain monoglycerides can be used alone as a primary solubilizer or in conjunction, as an emulsifier, with other ABITEC ingredients. 

Product Name Chemical Name CAS Number
Capmul GML-90 NF Glyceryl monolaurate  142-18-7
Capmul PG-8 NF Propylene Glycol Monocaprylate 68332-79-6
Capmul PG-8-70 NF Propylene Glycol Monocaprylate, NF Type 1 68332-79-6
Capmul PG-12 EP/NF Propylene Glycol Monolaurate 27194-74-7

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Captex medium-chain esters are preferred lipophilic vehicles and solvents, used alone or in combination with other excipients, in the development of solution, suspension, emulsion and microemulsion formulations for various delivery systems.

Product Name Chemical Name CAS Number
Captex 170 EP Caprylic/Capric Acid Ester of Saturated Fatty Alcohol C12-C18 95912-86-0
Captex 200P Propylene Glycol Dicaprylocaprate 68583-51-7
Captex 300 EP/NF Glyceryl Tricaprylate/Tricaprate 65381-09-1
Captex 355 EP/NF Glycerol Tricaprylate/Caprate 65381-09-1,
Captex 8000 Glyceryl Tricaprylate 538-23-8


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Acconon excipients are well-characterized mixtures of polyoxyethylene mono- and diglycerides, fatty acids or fatty alcohols. They are used to improve the bioavailability of poorly soluble drugs by direct solubilization or by acting as a stabilizing surfactant in active carrying emulsions.

Product Name Chemical Name CAS Number
Acconon AKG-6 EP/NF* Oleoyl Macrogolglycerides 69071-70-1
Acconon C-44 EP/NF* Lauroyl Macrogoglycerides 67701-26-2
Acconon C-50 EP/NF* Stearoyl Macrogolglycerides or Stearoyl Polyoxylglycerides  
Acconon MC8-2 EP/NF Polyoxyethylene (8) Caprylic/Capric Glycerides 91744-32-0, 223129-75-7


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Hydro~Kote hydrogenated vegetable oils are refined, bleached, and deodorized. Their unique properties make them very useful in topical creams and ointments for the pharmaceutical industry.

Product Name Chemical Name CAS Number
Hydro~Kote 112 Hydrogenated Palm Kernel Oil, and soy lecithin 68334-28-1, 8002-43-5
Hydro~Kote C Hydrogenated Cottenseed Oil 68334-00-9
Hydro~Kote M Hydrogenated Palm Kernel Oil, and soy lecithin 68334-28-1, 8002-43-5


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Related Applications

oral   suppositories   ophthalmic

Legal Disclaimer

CAPMUL®, CAPTEX®, ACCONON® and HYDO-KOTE® are registered trademarks of ABITEC Corporation.  All information and statements given on this website are believed to be accurate at the time of publication. However, neither ABITEC Corporation nor any of their affiliates make any representations or warranty with respect thereto, including, but not limited to, any results obtained in the processing of the products by customers or any third party. All information and statements are intended for persons having the required skill and know-how and do not relieve the customer or user from verifying the suitability of information and statements given for a specific purpose prior to use of the products. It is entirely the obligation of the customer or user to comply with applicable laws and regulations, and also with all patent or other intellectual property rights of third parties. ABITEC CORPORATION EXPRESSELY DISCLAIMS ANY REPRESENTATIONS OR WARRANTIES OF ANY KIND, WHETHER EXPRESSED OR IMPLIED, AS TO THE ACCURACY, CURRENCY, COMPLETENESS AND/OR THE MERCHANTABILITY OR FITNESS OF A PARTICULAR PURPOSE OF ANY INFORMATION CONTAINED ON THIS WEBSITE AND/OR PRODUCT DESCRIBED OR PROMOTED ON THIS WEBSITE, INCLUDING WARRANTIES WITH RESPECT TO INFRINGEMENT OF ANY PATENT, COPYRIGHT, OR OTHER RIGHTS OF A THIRD PARTY. We reserve the right to change product specifications and specified properties of the products without prior notice.