Lipid-based Drug Delivery of Cannabinoids

12/15/2023 - 12/15/2023

While per-oral delivery is the patient-preferred route of administration, the per-oral dosing of cannabinoid actives is not trivial. Due to low solubility and extensive first pass metabolism, the per-oral dosing of cannabinoid actives often results in relatively low bioavailability. Lipid-based drug delivery, including self-emulsifying drug delivery, readily provides for improved per-oral solubility and bioavailability of cannabinoid actives, increasing the therapeutic effectiveness of these products.

Key Learning Objectives

  • How lipids improve the per-oral solubility and bioavailability of cannabinoids
  • How to formulate self-emulsifying cannabinoid delivery systems
  • How to analyze emulsion characteristics

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Webinar Speakers

John Tillotson R.Ph., Ph.D.
Technical Business Director, Canada, Latin American and India
ABITEC Corporation

John joined ABITEC Corporation in 2015 and he is responsible for business development and product technical support in the US, Canada, Latin America, and India. He has extensive experience in the development of lipid-based drug delivery systems including self-emulsifying drug delivery systems, cannabinoid lipid-based drug delivery systems, co-processed lipid preconcentrates, and topical self-emulsifying formulations. He has extensive experience in the development of solid oral dosage forms, including the development of multiple direct-compression, drug delivery systems and formulations. He has developed multiple orally disintegrating excipient systems for both the nutraceutical and pharmaceutical industries, including a patented ODT excipient system. He has also developed excipient systems for the tableting of lipids. He has a B.S. in Pharmacy from Ferris State University, MI, and a Ph.D. in Industrial Pharmacy from University of Cincinnati, OH.

Alice Hirschel, Ph.D.
Technical Business Director, Pharmaceutical and Nutritional Health
ABITEC Corporation

Dr. Alice Hirschel has 10 years of research in disease nutrient-interactions and 10 years product and commercial development experience in the food and nutrition industry. She graduated with a BS in Nutritional Sciences from the University of Georgia and a PhD in Nutritional Sciences from the University of Texas at Austin. Dr. Hirschel began formulating supplements as a Product Development Scientist at GNC. She transitioned to Commercial Development with Innophos Nutrition and now, Dr. Hirschel works in technical, commercial and business development, learning to execute sales and marketing strategies with ABITEC Corporation.